2022-23 Week 13B: Six Teams Move into Regional Semifinals
Winning San Diego teams highlighted.
BOYS QUARTERFINALS
| DIVISION | TEAM/VISITOR | SEED | OPPONENT/HOME | SEED | SCORE |
| Open | St. Augustine (27-4) | 4 | Valencia West Ranch | 5 | 63-60 |
| III | Lincoln (30-3) | 10 | Culver City (19-12) | 2 | 82-77, OT. |
| San Luis Obispo Mission Prep (23-9) | 11 | Mission Bay (24-10) | 3 | 67-57 | |
| Ventura Buena (29-5) | 8 | La Jolla Country Day (24-8) | 1 | 48-44 | |
| IV | Victory Christian (24-9) | 6 | Ventura St. Bonaventure (25-9) | 3 | 59-48 |
| V | Cerritos Whitney (22-10) | 11 | Ramona (22-10) | 3 | 77-59 |
GIRLS QUARTERFINALS
| DIVISION | TEAM/VISITOR | SEED | TEAM/HOME | SEED | SCORE |
| Open | La Jolla Country Day (29-3) | 2 | Bye | ||
| I | Del Norte (22-10) | 5 | Mission Hills (22-12) | 4 | 61-57 |
| Mount Miguel (25-7) | 14 | Granada Hills Charter (26-6) | 11 | 53-45 | |
| II | La Canada Flintridge (30-3) | 8 | Bonita Vista (22-9) | 1 | 93-61 |
| III | Oak Park (22-11) | 11 | Cathedral (15-14) | 3 | 60-51 |
| IV | Oceanside (22-8) | 5 | Victorville Silverado (21-3) | 4 | 72-58 |